At the 73rd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) in Chicago, we showed the first ever 3D reconstruction of the complete brain of a living human being* from magnetic resonance imaging (MRI) as a poster and a video. Here are two short sequences from the original video.
The underlying MRI image volumes have a resolution of 256 x 256 x 128 voxels. They were acquired with a Siemens Magnetom, using Fast Low Angle Shot Imaging (FLASH) and Fast Imaging with Steady-state Precession (FISP) MRI sequences.
The images were produced with the VOXEL-MAN-8 program on a DEC VAX-11/780 minicomputer with connected Comtal Vision One and VTE Picturecom image processing systems. Detection of the contours of the brain with a 3D Marr-Hildreth operator took about 90 minutes. Calculation of a single 3D image from this dataset with a resolution of 256 x 256 pixels again took several minutes, so that the video required several days of computing time.
In the video, the flattening of the gyri in the right hemisphere due to a tumor (blue) and an edema (yellow) are clearly visible. The original gray values from FLASH and FISP images as well as the first principal component of the Karhunen-Loeve transform (KL-TR) are mapped on the cut planes, emphasizing different aspects of the pathology.
This work was awarded the DAGM Price 1987 of the German Association for Pattern Recognition.
*To our best knowledge.
- Michael Bomans, Karl Heinz Höhne, Ulf Tiede, Martin Riemer: 3-D segmentation of MR images of the head for 3-D display. IEEE Transactions on Medical Imaging 9, 2 (1990), 177-183.
- Michael Bomans, Martin Riemer, Ulf Tiede, Karl Heinz Höhne: 3-D Segmentation von Kernspin-Tomogrammen. In E. Paulus (Hrsg.): Mustererkennung 1987, Proc. 9. DAGM-Symposium, Informatik-Fachberichte 149, Springer-Verlag, Berlin, 1987, 231-235.
- Karl Heinz Höhne, Ulf Tiede, Martin Riemer, Michael Bomans, Martin Heller, Gerd Witte: Static and dynamic three-dimensional display of tissue structures from volume scans. Radiology 165, P (1987), 420.
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